Product Overview
DeNovo® NT Graft is a particulated juvenile cartilage implant used for the repair of articular cartilage damage. It is intended to provide surgeons with an early-intervention option for articular cartilage repair and cartilage restoration.
Advantages of using DeNovo NT Graft include:
• Juvenile tissue has 10x greater chondrocyte density than adult tissue and does not elicit an allogeneic immune response
• The graft is implanted in a single stage procedure with fibrin fixation.
• No need to harvest a periosteal flap.
• No need to harvest tissue or cells from areas of undamaged cartilage.
DeNovo NT Graft is an FDA-listed tissue product used for knee, hip, ankle and shoulder cartilage restoration since 2007 with over 6,000 surgeries completed. There have been no reports of graft rejection or disease transmission.
A study of 25 subjects with knee cartilage lesions treated with DeNovo NT Graft demonstrated that patients experienced a significant reduction in symptoms associated with cartilage damage, including knee pain, and improvement in function and sports activities for at least two years following surgery(*p<0.05). (https://www.zimmerbiomet.com)
